Adavivint
Alaye ọja
ọja Tags
| Iwọn Pack | Wiwa | Iye owo (USD) |
| 100mg | O wa | 500 |
| 500mg | O wa | 800 |
| 1g | O wa | 1200 |
| Awọn iwọn diẹ sii | Gba Awọn asọye | Gba Awọn asọye |
Orukọ Kemikali:
N-(5-{3-[7-(3-fluorophenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-5-yl}pyridin-3-yl)-3 -methylbutanamide
KỌỌDỌ SMILES:
CC(C)CC(NC1=CC(C2=CC3=C(NN=C3C(N4)=NC5=C4C(C6=CC=CC(F)=C6)=CN=C5)C=C2)=CN= C1)=O
Koodu InChi:
InChi=1S/C29H24FN7O/c1-16(2)8-26(38)33-21-10-19(12-31-13-21)17-6-7-24-22(11-17)28( 37-36-24)29-34 -25-15-32-14-23(27 (25)35-29)18-4-3-5-20(30)9-18/h3-7,9-16H,8H2,1-2H3,( H,33,38)(H,34,35)(H,36,37)
Bọtini InChi:
AQDWDWAYVBQMAM-UHFFFAOYSA-N
Koko-ọrọ:
Adavivint, SM04690, SM-04690, SM 04690, 1467093-03-3
Solubility:Tiotuka ni DMSO
Ibi ipamọ:0 - 4°C fun igba kukuru (ọjọ si awọn ọsẹ), tabi -20°C fun igba pipẹ (osu).
Apejuwe:
A aramada kekere moleku Wnt inhibitor ipa ọna pẹlu EC50 ti 3 nM in vitro; fa iyatọ hMSC sinu ogbo, chondrocytes iṣẹ ṣiṣe ati dinku awọn ipele ami ami catabolic kerekere; ni pataki ilọsiwaju Osteoarthritis Research Society International (OARSI) awọn iṣiro itan-akọọlẹ ati awọn ami-ara ni awoṣe OA rodent.
afojusun: WNT
