PI3K

Ologbo #	Orukọ ọja	Apejuwe
CPD1573	GDC-0077	GDC-0077 jẹ inhibitor PI3K ti o wa ni ẹnu pẹlu iṣẹ ṣiṣe antineoplastic ti o pọju.
CPD1022	IPI-549	IPI549 jẹ oludaniloju PI3Kγ ti o lagbara ati yiyan pẹlu IC50 ti 16 nM.
CPDD3857	GDC-0326	GDC-0326 jẹ oludena ti o lagbara ati yiyan ti α-Isoform of Phosphoinotide 3-Kinase (pi3Kalpha inhibitor). GDC-0326 ṣe aṣeyọri ipele giga pupọ ti yiyan lori awọn kinases miiran. GDC-0326 ni pilasima CL kekere ninu eniyan.
CPDB0202	AZD8186	AZD8186 jẹ ati inhibitor ti isoform beta ti phosphoinotide-3 kinase (PI3K), pẹlu iṣẹ ṣiṣe antineoplastic ti o pọju.
CPDB1536	PQR530	PQR530 jẹ oludena pan-PI3K/mTORC1/2 meji ti o lagbara pupọ.
CPDB1573	GDC-0077	GDC-0077 jẹ ẹnu ti o wa ni ẹnu ati yiyan PI3K inhibitor (IC50 = 0.038 + 0.003 nM) pẹlu> 300-agbo yiyan lori awọn isoforms Kilasi I PI3K miiran.