Ifebemtinib，BI 853520

Kimyoviy nomi:

4-[[4-[(2,3-Dihidro-2-metil-3-okso-1H-izoindol-4-il)oksi]-5-(triflorometil)-2-pirimidinil]amino]-2-ftor- 5-metoksi-N-(1-metil-4-piperidinil)benzamid

SMILE kodi:

O=C(NC1CCN(C)CC1)C2=CC(OC)=C(NC3=NC=C(C(F)(F)F)C(OC4=CC=CC(CN5C)=C4C5=O)= N3)C=C2F

InChi kodi:

InChI=1S/C28H28F4N6O4/c1-37-9-7-16(8-10-37)34-24(39)17-11-22(41-3)20(12-19(17)29)35- 27-33-13-18(28(30,31)32)25(36-27)42-21-6-4-5-15-14-38(2)26(40)23(15)21/ h4-6,11-13,16H,7-10,14H2,1-3H3,(H,34,39)(H,33,35,36)

InChi kaliti:

ULMMVBPTWVRPSI-UHFFFAOYSA-N

Kalit so'z:

1227948-82-4;CAS:1227948-82-4;CAS:1227948-82-4;Ifebemtinib;BI 853520

Eruvchanligi:Suvda emas, DMSO da eriydi

Saqlash:Qisqa muddatli (kunlardan haftagacha) 0 - 4 C yoki uzoq muddatli (oylar) uchun -20 C.

Tavsif:

Ifebemtinib (BI 853520) og'iz faoliyati bilan fokal adezyon kinazning (FAK) kuchli inhibitoridir.

Maqsad: FAK kuchli inhibitori