BN104

Kimyoviy nomi:

(2-(6-(2-(4-siklopropilpirimidin-5-il)-4-fluorofenoksi)-1,2,4-triazin-5-il)-2,7-diazaspiro[3.5]nonan-7-il )((1S,3aR,6aS)-oktahidrotsiklopenta[c]pirol-1-il)metanon

SMILE kodi:

[H][C@@]12CCC[C@]1([H])[C@H](NC2)C(=O)N3CCC4(CN(C4)C5=C(OC6=CC=C(F) C=C6C7=CN=CN=C7C8CC8)N=NC=N5)CC3

InChi kodi:

1S/C31H35FN8O2/c32-21-6-7-25(23(12-21)24-14-33-17-35-26(24)19-4-5-19)42-29-28(36-) 18-37-38-29)40-15-31(16-40)8-10-39(11-9-31)30(41)27-22-3-1-2-20(22)13- 34-27/h6-7,12,14,17-20,22,27,34H,1-5,8-11,13,15-16H2/t20-,22-,27-/m0/s1

InChi kaliti:

XDXAYPYOHXUEAM-CLHVYKLBSA-N

Kalit so'z:

2938995-50-5;CAS:2938995-50-5;CAS:2938995-50-5;BN-104;BN104;BN 104

Eruvchanligi: 

Saqlash:Quruq, qorong'i va qisqa muddatli (kunlardan haftalargacha) 0 -4 C yoki uzoq muddatli (oylar va yillar) uchun -20 C da

Tavsif:

BN-104 (BNM-1192) Menin MLL o'zaro ta'sirini inhibe qilishi mumkin va o'tkir miyeloid leykemiya kabi saraton tadqiqotlarida foydalanish mumkin.

Maqsad: Menin-MLL