BMS-955176

BMS-955176
  • Nomi:BMS-955176
  • Katalog raqami:CPD3218
  • CAS raqami:1392312-45-6 (erkin baza) 2097784-79-5 (TFA)
  • Molekulyar og'irlik:690.44
  • Kimyoviy formula:C42H62N2O4S
  • Bemorlar uchun emas, faqat ilmiy tadqiqotlar uchun.

    Mahsulot detali

    Mahsulot teglari

    Paket hajmi Mavjudligi Narxi (AQSh dollari)

    Kimyoviy nomi:

    4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-((2-(1,1-dioksidotiomorfolino)etil)amino)-5a,5b,8,8,11a -pentametil-1 -(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-oktadekahidro -1H-siklopenta[a]xrizen-9-il)benzoy kislota

    SMILE kodi:

    O=C(O)C1=CC=C(C2=CC[C@@]3(C)[C@@](C2(C)C)([H])CC[C@@]4(C) )[C@]5(C)CC[C@](C C[C@H]6C(C)=C)(NCCN(CC7)CCS7(=O)=O)[C@@]6([H])[C@@]5([H])CC[ C@]34[H])C=C1

    InChi kodi:

    InChI=1S/C42H62N2O4S/c1-28(2)31-14-19-42(43-22-23-44-24-26-49(47,48)2 7-25-44)21-20-40(6)33(36(31)42)12-13-35-39(5)17-15-32(29-8-10-30(11-9) -29)37(45)46)38(3,4)34(39)16-18-41(35,40)7/h8-11,15,31,33-36,43H,1,12 -14,16-27H2,2-7H3,(H,45,46)/t31-,33+,34-,35+,36+,39-,40+,41+,42-/m0/s1

    InChi kaliti:

    XDMUFNNPLXHNKA-ZTESCHFWSA-N

    Kalit so'z:

    GSK3532795, GSK-3532795, GSK 3532795, BMS-955176, BMS 955176, BMS955176

    Eruvchanligi: 

    Saqlash: 

    Tavsif:

    BMS-955176 nomi bilan ham tanilgan GSK3532795 kuchli, og'iz orqali faol, ikkinchi avlod OIV-1 etuklashuv inhibitori (MI) bo'lib, IIb klinik sinovlari orqali rivojlangan. GSK3532795 polimorf viruslarning keng qamrovini birlashtiradi (EC50Klinikadan oldingi turlarda qulay farmakokinetik profilga ega 96,5% OIV-1 kichik turi B virusini ifodalovchi umumiy polimorfizmlar paneliga <15 nM.

    Maqsad: OIV-1 etuklik inhibitori (MI)


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