THZ2

THZ2
  • Lebitso:THZ2
  • Nomoro ea lethathamo:CPDB1587
  • Nomoro ea CAS:1604810-84-5
  • Boima ba Molek'hule:566.06
  • Foromo ea Lik'hemik'hale:C31H28ClN7O2
  • Bakeng sa lipatlisiso tsa saense feela, eseng bakeng sa bakuli.

    Lintlha tsa Sehlahisoa

    Li-tag tsa Sehlahisoa

    Boholo ba Pakete Ho fumaneha Theko (USD)
    100mg E teng thepeng e teng ka lebenkeleng 500
    500mg E teng thepeng e teng ka lebenkeleng 800
    1g E teng thepeng e teng ka lebenkeleng 1200
    Boholo bo Eketsehileng Fumana Litlhaloso Fumana Litlhaloso

    Lebitso la lik'hemik'hale:

    N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]-3-[[(E)-4-(dimethylamino)empa-2- enoyl]amino]benzamide

    SMILES Khouto:

    O=C(NC1=CC=CC(NC2=NC=C(Cl)C(C3=CNC4=C3C=CC=C4)=N2)=C1)C5=CC=CC(NC(/C=C/CN (C)C)=O)=C5

    Khoutu ea InChi:

    InChI=1S/C31H28ClN7O2/c1-39(2)15-7-14-28(40)35-21-9-5-8-20(16-21)30(41)36-22-10-6- 11-23(17-22)37-31-34-19-26 (32)29(38-31)25-18-33-27-13-4-3-12-24(25)27/h3-14,16-19,33H,15H2,1-2H3,(H, 35,40)(H,36,41)(H,34,37,38)/b14-7+

    InChi Key:

    FONRCZUZCHXWBD-VGOFMYFVSA-N

    Keyword:

    THZ-2, THZ 2, THZ2, 1604810-84-5

    Sollubility:E qhibiliha ka DMSO

    Polokelo:0 - 4 ° C bakeng sa nako e khutšoanyane (matsatsi ho isa libeke), kapa -20 ° C bakeng sa nako e telele (likhoeli).

    Tlhaloso:

    THZ2, analoge ea THZ1, e nang le monyetla oa ho phekola mofetše oa matsoele oa Triple-negative (TNBC), ke CDK7 inhibitor e matla le e khethang e hlolang ho se tsitse ha THZ1 ka vivo. IC50: CDK7 = 13.9 nM; Lisele tsa TNBC= 10 nM

    Sepheo: CDK


  • E fetileng:
  • E 'ngoe:

  • Lihlahisoa tse Amanang

    .
    Moqoqo oa Marang-rang oa WhatsApp!