in vivo Pharmacokinetic Assays

Sehlopha sa rona sa pharmacokinetic se sebetsa ka ho khetheha ho nts'etsopele ea pele, tlhahlobo ea DMPK le ngoliso ea IND. Re thehile sethala se kopaneng sa in vitro & in vivo screening technology ho ts'ehetsa ho sibolloa le nts'etsopele ea lithethefatsi. Caerulum Pharma e fana ka litšebeletso tse feto-fetohang le tsa motho ka mong bakeng sa tharollo ea DMPK e sebetsang hantle le e theko e tlaase.

1.Likarolo tsa thuto

Limolek'hule tse nyane, lihlahisoa tsa tlhaho, polypeptides.

2.Litšebeletso tse teng

Litlhahlobo tse potlakileng tsa PK ka litsela tse fapaneng tsa tsamaiso mefuteng ea litoeba le tse se nang likhoto, joalo ka litoeba, likhoto, ntja le litšoene.

Kabo ea lisele

Excretion le boima ba boima

Mohlala oa CSF le ho kenella ha BBB

Ntlafatso ea mokhoa oa ho hlahloba ka har'a matrix a baeloji

Tlhahlobo ea palo ea lisampole tse fapaneng tsa baeloji

Ts'ebetso ea data le ho tsamaisoa

3.DMPK e amanang le moralo le ts'ebetso ea protocol e ipapisitseng le tlhokahalo e boletsoeng ea thuto.


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