KATSE # | Lebitso la Sehlahiswa | Tlhaloso |
CPDD3529 | PRT-060318; PRT318; P142–76 | PRT060318 ke inhibitor e matla le e khethollang ea spleen tyrosine kinase (Syk; IC50 = 4 nM). E khetha, e thibela 92% ea ts'ebetso ea Syk, ha li-kinase tse ling li boloka> 70% ts'ebetso, ka bongata ba 50 nM ka phanele ea Lik'hilograma tse 270. |
CPDD1851 | BAY 61-3606 2HCl | BAY 61-3606 ke e matla (Ki = 7.5 nM) le inhibitor e khethiloeng ea Syk kinase. |