| KATSE # | Lebitso la Sehlahiswa | Tlhaloso |
| CPD100464 | Erdafitinib | Erdafitinib, eo hape e tsejoang e le JNJ-42756493, ke inhibitor e matla le e khethang ea molomo, pan fibroblast growth factor receptor (FGFR) inhibitor e nang le ts'ebetso e ka bang teng ea antineoplastic. Ha e sebelisoa ka molomo, JNJ-42756493 e tlama le ho thibela FGFR, e ka 'nang ea fella ka ho thibela litsela tse amanang le FGFR tse amanang le ho fetisa matšoao 'me kahoo ho thibela ho ata ha lisele tsa tumor le lefu la lisele tsa tumor ho FGFR-overexpressing lisele tsa tumor. FGFR, e laoloang ke mefuta e mengata ea lisele tsa tumor, ke receptor tyrosine kinase e hlokahalang bakeng sa ho ata ha lisele tsa tumor, ho arohana le ho phela. |
| CPD3618 | TAS-120 | TAS-120 ke inhibitor ea molomo ea bioavailable ea fibroblast growth factor receptor (FGFR) e nang le ts'ebetso e ka bang teng ea antineoplastic. FGFR inhibitor TAS-120 ka boikhethelo le ka mokhoa o ke keng oa fetoloa e tlama le ho thibela FGFR, e ka 'nang ea fella ka ho thibela tsela ea phetisetso ea matšoao a mabeli a FGFR le ho ata ha lisele tsa tumor, le ho eketsa lefu la lisele ho FGFR-overexpressing lisele tsa tumor. FGFR ke receptor tyrosine kinase e hlokahalang bakeng sa ho ata ha lisele tsa tumor, ho arohana le ho phela 'me polelo ea eona e laoloa ke mefuta e mengata ea lisele tsa tumor. |
| CPDB1093 | Derazantinib; ARQ-087 | Derazantinib, e tsejoang hape e le ARQ-087, ke inhibitor ea molomo ea bioavailable ea fibroblast growth factor receptor (FGFR) e nang le ts'ebetso e ka bang teng ea antineoplastic. |
| CPDB0942 | BLU-554 | BLU-554 ke fibroblast growth factor receptor 4 (FGFR4) inhibitor e ka 'nang ea e-ba teng bakeng sa phekolo ea hepatocellular carcinoma le cholangiocarcinoma. |
| CPD0999 | H3B-6527 | H3B-6527 (H3 Biomedicine) ke FGFR4 inhibitor e khethiloeng ka ho fetisisa e nang le ts'ebetso e matla ea antitumour ho FGF19 amplified cell line le litoeba. |
| CPD0997 | FGF401 | FGF-401 ke inhibitor ea FGFR4 e ntšitsoeng ho patent WO2015059668A1, mohlala oa motsoako 83; e na le IC50 ea 1.9 nM. |
| CPDB0053 | AZD4547 | AZD 4547 ke inhibitor e khethiloeng ea fibroblast growth factor receptor (FGFR) tyrosine kinase e nang le litekanyetso tsa IC50 tsa 0.2, 2.5, le 1.8 nM bakeng sa FGFR1, 2, le 3, ka ho latellana. |
| CPD3610 | BLU-9931 | BLU9931 ke FGFR4 inhibitor e matla, e khethang, e ke keng ea fetoloa e nang le IC50 ea 3 nM, e ka bang 297-, 184-, le 50-fold selectivity ho feta FGFR1/2/3, ka ho latellana. |
