ARS-1630
Bakeng sa lipatlisiso tsa saense feela, eseng bakeng sa bakuli.
Lintlha tsa Sehlahisoa
Li-tag tsa Sehlahisoa
| Boholo ba Pakete | Ho fumaneha | Theko (USD) |
| 100mg | E teng thepeng e teng ka lebenkeleng | 800 |
| 500mg | E teng thepeng e teng ka lebenkeleng | 1500 |
| 1g | E teng thepeng e teng ka lebenkeleng | 2000 |
| Boholo bo Eketsehileng | Fumana Litlhaloso | Fumana Litlhaloso |
Lebitso la lik'hemik'hale:
(R)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one
SMILES Khouto:
"C=CC(N1CCN(C2=C3C=C(Cl)[C@@]([C@@]4=C(O)C=CC=C4F)=C(F)C3=NC=N2)CC1 )=O.[R]
Khoutu ea InChi:
InChi Key:
Keyword:
ARS1630, ARS 1630, ARS-1630, 1698055-86-5
Sollubility:E qhibiliha ka DMSO
Polokelo:0 - 4 ° C bakeng sa nako e khutšoanyane (matsatsi ho isa libeke), kapa -20 ° C bakeng sa nako e telele (likhoeli)
Tlhaloso:
ARS-1630 ke R-conformational atropisomer ea ARS-1620, ka makhetlo a 1,000 ka tlaase ho matla ho feta ARS-1620 (1.2 ± 0.6 M-1s-1) 'me kahoo e sebetsa e le motsoako o ikhethang oa taolo o sa sebetseng.
Sepheo: KRAS (K-Ras G12C)
