IT-901
Lintlha tsa Sehlahisoa
Li-tag tsa Sehlahisoa
| Boholo ba Pakete | Ho fumaneha | Theko (USD) |
| 100mg | E teng thepeng e teng ka lebenkeleng | 500 |
| 500mg | E teng thepeng e teng ka lebenkeleng | 800 |
| 1g | E teng thepeng e teng ka lebenkeleng | 1200 |
| Boholo bo Eketsehileng | Fumana Litlhaloso | Fumana Litlhaloso |
Lebitso la lik'hemik'hale:
5 - [(2,4-Dimethoxy-1-naphthalenyl)methylene]dihydro-2-thioxo-4,6(1H,5H) -pyrimidinedione
SMILES Khouto:
O=C(/C(C(N1)=O)=CC2=C3C=CC=CC3=C(OC)C=C2OC)NC1=S
Khoutu ea InChi:
InChI=1S/C17H14N2O4S/c1-22-13-8-14(23-2)11(9-5-3-4-6-10(9)13)7 -12-15(20)18-17(24)19-16(12)21/h3-8H,1-2H3,(H2,18,19,20,21,24)
InChi Key:
JHOPCCOYRKEHQU-UHFFFAOYSA-N
Keyword:
IT-901, IT901, IT 901, 1584121-99-2
Sollubility:E qhibiliha ka DMSO
Polokelo:0 - 4 ° C bakeng sa nako e khutšoanyane (matsatsi ho isa libeke), kapa -20 ° C bakeng sa nako e telele (likhoeli).
Tlhaloso:
"IT-901 ke c-Rel Inhibitor E Etsang Mekhatlo ea Anticancer in Hematologic Malignancies ka ho thibela NF-κB-Controlled Oxidative Stress Responses. IT-901 e thibela ka matla karolo ea NF-κB c-Rel. lefu la sets'oants'o ha o ntse o boloka ts'ebetso ea graft-versus-lymphoma nakong ea allogeneic Tlhahlobo e eketsehileng ea pele ea IT-901 bakeng sa phekolo ea B-cell lymphoma ea motho e senotse thepa ea antitumor in vitro le vivo ntle le thibelo ho NF-κB-e itšetlehileng ka lymphoma ha ea ka ea etsa hore ho be le mefuta e mengata ea oksijene e sebetsang ka mokhoa o tloaelehileng leukocyte, e bonts'ang thepa ea eona ea ho khetha mofetše IT-901 ke moemeli oa kalafo oa ho phekola lihlahala tsa lymphoid tsa batho fokotsa lefu la graft-versus-host ".
Sepheo: NF-kB
