ARS-1323

ARS-1323
  • Lebitso:ARS-1323
  • Nomoro ea lethathamo:CPDB2015
  • Nomoro ea CAS:1698024-73-5
  • Boima ba Molek'hule:430.84
  • Foromo ea Lik'hemik'hale:C21H17ClF2N4O2
  • Bakeng sa lipatlisiso tsa saense feela, eseng bakeng sa bakuli.

    Lintlha tsa Sehlahisoa

    Li-tag tsa Sehlahisoa

    Boholo ba Pakete Ho fumaneha Theko (USD)
    100mg E teng thepeng e teng ka lebenkeleng 500
    500mg E teng thepeng e teng ka lebenkeleng 800
    1g E teng thepeng e teng ka lebenkeleng 1200
    Boholo bo Eketsehileng Fumana Litlhaloso Fumana Litlhaloso

    Lebitso la lik'hemik'hale:

    1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one

    SMILES Khouto:

    O=C(C=C)N1CCN(C2=NC=NC3=C2C=C(Cl)C(C4=C(O)C=CC=C4F)=C3F)CC1

    Khoutu ea InChi:

    InChI=1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17(19(24)20(12)25- 11-26-21)18-14(23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2

    InChi Key:

    ZRPZPNYZFSJUPA-UHFFFAOYSA-N

    Keyword:

    ARS1323,ARS 1323,ARS-1323, 1698024-73-5

    Sollubility:E qhibiliha ka DMSO

    Polokelo:0 - 4 ° C bakeng sa nako e khutšoanyane (matsatsi ho isa libeke), kapa -20 ° C bakeng sa nako e telele (likhoeli)

    Tlhaloso:

    ARS-1323 ke inhibitor e ncha ea mutant K-ras G12C e nkiloeng ho patent WO 2015054572 A1. IC50 & Sepheo: K-Ras G12C

    Sepheo: KRAS (K-Ras G12C)


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