EAI-045
Product Detail
Product Tags
| Pack Saizi | Kuwanikwa | Mutengo (USD) |
Chemical Name:
2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide
SMILES Kodhi:
O=C(NC1=NC=CS1)C(C2=CC(F)=CC=C2O)N3CC4=C(C=CC=C4)C3=O
InChi Code:
InChI=1S/C19H14FN3O3S/c20-12-5-6-15(24)14(9-12)16(17(25)22-19-21-7-8 -27-19)23-10-11-3-1-2-4-13(11)18(23)26/h1-9,16,24H,10H2,(H,21,22,25)
InChi Key:
YTUFHOKUFOQRDF-UHFFFAOYSA-N
Keyword:
EAI-045, EAI045, EAI 045, 1942114-09-1
Solubility:Soluble muDMSO
Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi)
Tsanangudzo:
EAI045 ia ine simba uye inosarudza EGFR inhbitor. EAI045 inonangwa yakasarudza EGFR isingaite mushonga asi inochengetedza mhuka yemusango inogamuchira. EAI045 inhibits L858R/T790M-mutant EGFR ine yakaderera-nanomolar potency mu biochemical assays.
Chinangwa: EGFR
