Osimertinib Mesylate

Osimertinib Mesylate
  • Zita:AZD-9291 (Mesylate); Tagrisso; Osimertinib Mesylate
  • Catalog Nhamba:CPDB0137
  • Nhamba yeCAS:1421373-66-1
  • Molecular Weight:595.72
  • Chemical Formula:C29H37N7O5S
  • Kutsvakurudza kwesayenzi chete, kwete kuvarwere.

    Product Detail

    Product Tags

    Pack Saizi Kuwanikwa Mutengo (USD)
    500mg Mudura 100
    1g Mudura 180
    5g Mudura 600
    Mamwe Saizi Wana MaQuotes Wana MaQuotes

    Chemical Name:

    N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino )phenyl)acrylamide mesylate

    SMILES Kodhi:

    CN(CCN(C)C)C1=CC(OC)=C(C=C1NC(C=C)=O)NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2 .OS(=O)(C)=O

    InChi Code:

    InChI=1S/C28H33N7O2.CH4O3S/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3) 32-28-29-13-12-21(31-28 )20-18-35(5)24-11-9-8-10-19(20)24;1-5(2,3)4/h7-13,16-18H,1,14-15H2,2 -6H3,(H,30,36)(H,29,31,32);1H3,(H,2,3,4)

    InChi Key:

    FUKSNUHSJBTCFJ-UHFFFAOYSA-N

    Keyword:

    AZD-9291, AZD9291, AZD 9291, Tagrisso,Osimertinib Mesylate, 1421373-66-1

    Solubility:Soluble muDMSO

    Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi)

    Tsanangudzo:

    Osimertinib, inozivikanwawo semereletinib uye AZD-9291, chizvarwa chechitatu cheEGFR inhibitor, yakaratidza chivimbiso muzvidzidzo zvepakutanga uye inopa tariro kune varwere vane kenza yemapapu yepamusoro iyo yave isingagadziriki kune EGFR inhibitors iripo. AZD9291 inoshanda zvakanyanya mumhando dzepreclinical uye inotenderwa mumhando dzemhuka. Inodzivisa zvose zvinogadzirisa uye zvinopesana nekuchinja kweEGFR uku uchichengetedza chimiro cheEGFR chiripo mumasero eganda uye mumatumbo, nokudaro kuderedza migumisiro yakasangana nemishonga iripo ikozvino. Osimertinib yakatenderwa muna Nov. 2015.

    Chinangwa: EGFR


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