Osimertinib Mesylate
Product Detail
Product Tags
Pack Saizi | Kuwanikwa | Mutengo (USD) |
500mg | Mudura | 100 |
1g | Mudura | 180 |
5g | Mudura | 600 |
Mamwe Saizi | Wana MaQuotes | Wana MaQuotes |
Chemical Name:
N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino )phenyl)acrylamide mesylate
SMILES Kodhi:
CN(CCN(C)C)C1=CC(OC)=C(C=C1NC(C=C)=O)NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2 .OS(=O)(C)=O
InChi Code:
InChI=1S/C28H33N7O2.CH4O3S/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3) 32-28-29-13-12-21(31-28 )20-18-35(5)24-11-9-8-10-19(20)24;1-5(2,3)4/h7-13,16-18H,1,14-15H2,2 -6H3,(H,30,36)(H,29,31,32);1H3,(H,2,3,4)
InChi Key:
FUKSNUHSJBTCFJ-UHFFFAOYSA-N
Keyword:
AZD-9291, AZD9291, AZD 9291, Tagrisso,Osimertinib Mesylate, 1421373-66-1
Solubility:Soluble muDMSO
Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi)
Tsanangudzo:
Osimertinib, inozivikanwawo semereletinib uye AZD-9291, chizvarwa chechitatu cheEGFR inhibitor, yakaratidza chivimbiso muzvidzidzo zvepakutanga uye inopa tariro kune varwere vane kenza yemapapu yepamusoro iyo yave isingagadziriki kune EGFR inhibitors iripo. AZD9291 inoshanda zvakanyanya mumhando dzepreclinical uye inotenderwa mumhando dzemhuka. Inodzivisa zvose zvinogadzirisa uye zvinopesana nekuchinja kweEGFR uku uchichengetedza chimiro cheEGFR chiripo mumasero eganda uye mumatumbo, nokudaro kuderedza migumisiro yakasangana nemishonga iripo ikozvino. Osimertinib yakatenderwa muna Nov. 2015.
Chinangwa: EGFR