AMG-510

AMG-510
  • Zita:AMG-510
  • Catalog Nhamba:CPD2809
  • Nhamba yeCAS:2296729-00-3, (2252403-56-6 racemate)
  • Molecular Weight:560.23
  • Chemical Formula:C30H30F2N6O3
  • Kutsvakurudza kwesayenzi chete, kwete kuvarwere.

    Product Detail

    Product Tags

    Pack Saizi Kuwanikwa Mutengo (USD)
    1g mudura 1300
    5g mudura 6000
    10g mudura 10500

    Chemical Name:

    4-((S)-4-acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl) )pyrido[2,3-d]pyrimidin-2(1H)-imwe

    SMILES Kodhi:

    O=C(C=C)N1C[C@H](C)N(C2=NC(N(C3=C(C)C=CN=C3C(C)C)C4=C2C=C(F)C (C5=C(O)C=CC=C5F)=N4)=O)CC1

    InChi Code:

    InChI=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8- 7-9-22(24)39)34 -29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6-11,14,16,18,39H,1 ,12-13,15H2,2-5H3/t18-/m0/s1

    InChi Key:

    NXQKSXLFSAEQCZ-SFHVURJKSA-N

    Keyword:

    AMG-510; AMG 510; AMG510

    Solubility: 

    Kuchengeta: 

    Tsanangudzo:

    AMG-510 ine simba KRAS G12C covalent inhibitor. AMG-510 yakanangana neiyo KRAS p.G12C inoshanduka, ingave iyo DNA, RNA kana protein level, uye inodzivirira, nenzira isati yanyatsojekeswa, kutaura uye/kana tumor cell kusaina kuburikidza neKRAS p.G12C mutant. Izvi zvinogona kutadzisa kukura muKRAS p.G12C-inoratidza bundu maseru

    Chinangwa: KRAS


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