Omarigliptin
Fa'amatalaga Oloa
Faailoga o oloa
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Igoa vaila'au:
(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)tetrahydro-2H -pyran-3-amine
SMILES Code:
N[C@@H]1[C@@H](C2=CC(F)=CC=C2F)OC[C@H](N3CC4=NN(S(=O)(C)=O)C= C4C3)C1
InChi Code:
InChI=1S/C17H20F2N4O3S/c1-27(24,25)23-7-10-6-22(8-16(10)21-23)12-5-15(20)17(26-9) -12)13-4-11(18)2-3-14(13)19/h2-4,7,12,15,17H,5-6,8-9,20H2,1H3/t12-,15+ ,17-/m1/s1
InChi Key:
MKMPWKUAHLTIBJ-ISTRZQFTSA-N
upu autu:
Omarigliptin,MK-3102,MK3102,Marizev,1226781-44-7
Solubility:Solu i le DMSO
Teuina:0 - 4°C mo taimi pupuu (aso i vaiaso), po'o le -20°C mo taimi uumi (masina)
Fa'amatalaga:
Omarigliptin, fa'aigoaina MK-3102, ose fa'atosina malosi ma umi ona galue DPP-4 mo togafitiga ta'itasi vaiaso ole ma'isuka ituaiga 2. MK-3102 (omarigliptin), na faailoaina o se dipeptidyl peptidase 4 (DPP-4) inhibitor malosi ma filifili ma se talaaga lelei o le pharmacokinetic e mafai ona faʻaogaina i le vaiaso e tasi ma filifilia e avea ma sui o le atinaʻeina o falemaʻi. Omarigliptin o loʻo i ai nei i le vaega 3 o le atinaʻeina o falemaʻi.
Sini: DPP-4