Sitagliptin

Sitagliptin
  • Igoa:Sitagliptin
  • Numera fa'amaumauga:CPDA0100
  • Numera CAS:654671-77-9(Sitagliptin Phosphate Monohydrate); 654671-78-0 (Sitagliptin Phosphate ); 486460-32-6(faavae fua)
  • Molecular Weight:407.31
  • Fua Fa'atatau ole vaila'au:C16H15F6N5O
  • Mo na'o su'esu'ega fa'asaienisi, ae le mo gasegase.

    Fa'amatalaga Oloa

    Faailoga o oloa

    Tele o le afifi Avanoa Tau (USD)

    Igoa vaila'au:

    Sitagliptin (INN; na muai faailoaina o MK-0431 ma faʻatau atu i lalo o le igoa tau fefaʻatauaʻiga Januvia) o se vailaʻau faʻamaʻi faʻamaʻi (anti-diabetic drug) o le dipeptidyl peptidase-4 (DPP-4) inhibitor vasega.

    SMILES Code:

    O=C(N1CC2=NN=C(C(F)(F)F)N2CC1)C[C@H](N)CC3=CC(F)=C(F)C=C3F.O=P(O )(O)O.[H]O[H]

    InChi Code:

    InChI=1S/C16H15F6N5O.H3O4P.H2O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27- 13(7- 26)24-25-15(27)16(20,21)22;1-5(2,3)4;/h4,6,9H,1-3,5,7,23H2;(H3,1, 2,3,4);1H2/t9-;;/m1../s1

    InChi Key:

    GQPYTJVDPQTBQC-KLQYNRQASA-N

    upu autu:

    Sitagliptin,Sitagliptin phosphate,Januvia,Glactiv,ONO-5435, MK-0431, L-000224715, 654671-77-9,654671-78-0, 486460-32-6

    Solubility:Solu i le DMSO

    Teuina:0 - 4°C mo taimi pupuu (aso i vaiaso), poo le -20°C mo taimi uumi (masina).

    Fa'amatalaga:

    Sitagliptin (INN; na muai faailoaina o MK-0431 ma faʻatau atu i lalo o le igoa tau fefaʻatauaʻiga Januvia) o se vailaʻau faʻamaʻi faʻamaʻi (anti-diabetic drug) o le dipeptidyl peptidase-4 (DPP-4) inhibitor vasega. Na atiina ae ma maketi e Merck & Co. O lenei enzyme-inhibiting drug e faʻaaogaina pe naʻo le tuʻufaʻatasia ma isi vailaʻau antihyperglycemic oral (e pei o le metformin poʻo se thiazolidinedione) mo togafitiga o le maʻisuka ituaiga 2. O le aoga o lenei vailaʻau o le. ona a'afiaga pito maualalo (fa'ata'ita'iga, fa'aitiitia le hypoglycemia, fa'aitiitia le mamafa o le mamafa) i le fa'atonutonuina o le maualuga ole kulukose ile toto. Exenatide (Byetta) e galue foi i lona aafiaga i le incretin system.

    Sini: DPP-4


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