Ertugliflozin

Igoa vaila'au:

(1S,2S,3S,4R,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3 ,4-triol

SMILES Code:

"CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C34C(C(C(C(O3)(CO4)CO)O)O)O)Cl "

InChi Code:

"InChI=1S/C22H25ClO7/c1-2-28-16-6-3-13(4-7-16)9-14-10-15(5-8-17(14)23)22-20(27) )18(25)19(26)21(11-24,30-22)12-29-22/h3-8,10,18-20,24-27H,2,9,11-12H2,1H3/t18 -,19-,20+,21-,22-/m0/s1"

InChi Key:

"MCIACXAZCBVDEE-CUUWFGFTSA-N"

upu autu:

Ertugliflozin, PF 04971729,MK-8835,1210344-57-2

Solubility:Solu i le DMSO

Teuina:0 - 4°C mo taimi pupuu (aso i vaiaso), poo le -20°C mo taimi uumi (masina).

Fa'amatalaga:

O le Ertugliflozin, lea e lauiloa foi o le PF-04971729, o se inhibitor malosi ma le filifilia o le sodium-dependent glucose cotransporter 2 ma le fomaʻi mo togafitiga o le maʻisuka ituaiga 2. O suʻesuʻega faʻafomaʻi na faʻaalia ai o le Ertugliflozin (1-25 mg / aso) na faʻaleleia ai le pulea o le glycemic, mamafa o le tino ma le toto toto i tagata mamaʻi e maua i le T2DM i lalo o le puleaina o le metformin, ma sa talia lelei.

Sini: SGLT-2