CAT # | Izina ryibicuruzwa | Ibisobanuro |
CPD100230 | JBJ-04-125-02 R-isomer | |
CPD3232 | NTN21277 | NTN21277, izwi kandi nka PROTAC 3 ishingiye kuri Gefitinib ni PROTAC itoranya VHL itera kwangirika kwa EGFR na EGFR hamwe na DC50 ya 11.7 nM na 22.3 nM kuri selire HCC827 (Exon 19 del) na selire H3255 (L858R). |
CPDB3615 | Nazartinib; EGF816; NVS-816 | Nazartinib, izwi kandi nka EGF816 na NVS-816, ni umunwa uraboneka, udasubirwaho, igisekuru cya gatatu, mutant-selidive epidermal growth factor reseptor (EGFR) inhibitor, hamwe nibikorwa bya antineoplastique. |
CPDB0934 | EAI-045 | EAI045 ia inhbitor ya EGFR ikomeye kandi ihitamo. EAI045 yibasiye imiti ihindagurika ya EGFR irwanya ibiyobyabwenge ariko irinda imiti yo mu gasozi. EAI045 ibuza L858R / T790M-mutant EGFR hamwe nimbaraga nke za nanomolar mubushakashatsi bwibinyabuzima. |
CPDB0101 | Poziotinib | Imiti irimo poziotinib iri gukorwaho iperereza mu mavuriro yo kuvura EGFR-mutant ibihaha adenocarcinoma. |
CPDB0137 | Osimertinib Mesylate | Osimertinib, izwi kandi ku izina rya mereletinib na AZD-9291, ni igisekuru cya gatatu cya EGFR inhibitor, yerekanye amasezerano mu bushakashatsi bwibanze kandi itanga ibyiringiro ku barwayi bafite kanseri y'ibihaha yateye imbere barwanya indwara ya EGFR ihari. |