Osimertinib Mesylate
Ibicuruzwa birambuye
Ibicuruzwa
Ingano | Kuboneka | Igiciro (USD) |
500mg | Mububiko | 100 |
1g | Mububiko | 180 |
5g | Mububiko | 600 |
Ingano nini | Shaka Amagambo | Shaka Amagambo |
Izina ryimiti:
N- (2 - ((2- (dimethylamino) ethyl) (methyl) amino) -4-mikorerexy-5 - ((4- ) fenyl) acrylamide mesylate
Kode ya SMILES:
CN (CCN (C) C) C1 = CC (OC) = C (C = C1NC (C = C) = O) NC2 = NC = CC (C3 = CN (C) C4 = C3C = CC = C4) = N2 .OS (= O) (C) = O.
InChi Code:
InChI = 1S / C28H33N7O2.CH4O3S / c1-7-27 (36) 30-22-16-23 (26 (37-6) 17-25 (22) 34 (4) 15-14-33 (2) 3) 32-28-29-13-12-21 (31-28) 20-18-35 (5) 24-11-9-8-10-19 (20) 24; 1-5 (2,3) 4 / h7-13,16-18H, 1,14-15H2,2-6H3, (H, 30,36) (H, 29,31,32); 1H3, (H, 2,3,4)
InChi Urufunguzo:
FUKSNUHSJBTCFJ-UHFFFAOYSA-N
Ijambo ryibanze:
AZD-9291, AZD9291, AZD 9291, Tagrisso, Osimertinib Mesylate, 1421373-66-1
Gukemura:Gukemura muri DMSO
Ububiko:0 - 4 ° C mugihe gito (iminsi kugeza ibyumweru), cyangwa -20 ° C mugihe kirekire (amezi)
Ibisobanuro:
Osimertinib, izwi kandi ku izina rya mereletinib na AZD-9291, ni igisekuru cya gatatu cya EGFR inhibitor, yerekanye amasezerano mu bushakashatsi bwibanze kandi itanga ibyiringiro ku barwayi bafite kanseri y'ibihaha yateye imbere barwanya indwara ya EGFR ihari. AZD9291 ikora cyane muburyo bwa preclinical kandi irihanganirwa mubyitegererezo by'inyamaswa. Irabuza gukora no kurwanya ihindagurika rya EGFR mugihe irinze uburyo busanzwe bwa EGFR igaragara mu ngirabuzimafatizo zisanzwe z’uruhu n’inda, bityo bikagabanya ingaruka mbi zihura n’imiti iboneka ubu. Osimertinib yemejwe ku ya 2015 Ugushyingo.
Intego: EGFR