| CAT # | Izina ryibicuruzwa | Ibisobanuro |
| CPD100464 | Erdafitinib | Erdafitinib, izwi kandi nka JNJ-42756493, ni imbaraga zikomeye kandi zatoranijwe mu kanwa bioavailable, pan fibroblast growth factor reseptor (FGFR) inhibitor hamwe nibikorwa bya antineoplastique. Ku buyobozi bwo mu kanwa, JNJ-42756493 ihuza kandi ikabuza FGFR, ibyo bikaba byaviramo guhagarika inzira yo kwanduza ibimenyetso bifitanye isano na FGFR bityo bikabuza ikwirakwizwa ry’uturemangingo tw’ibibyimba ndetse n’urupfu rw’ibibyimba muri selile FGFR-bikabije bikabije. FGFR, igengwa nubwoko bwinshi bwibibyimba, ni reseptor tyrosine kinase ikenewe mugukwirakwiza ingirabuzimafatizo, gutandukanya no kubaho. |
| CPD3618 | TAS-120 | TAS-120 ni bioavailable yo mu kanwa ibuza fibroblast gukura kwakirwa (FGFR) hamwe nibikorwa bya antineoplastique. Inzitizi ya FGFR TAS-120 ihitamo kandi idasubirwaho ihuza kandi ikabuza FGFR, ibyo bikaba bishobora kuviramo guhagarika inzira yo gukwirakwiza ibimenyetso byifashishijwe na FGFR hamwe no gukwirakwiza ibibyimba, ndetse no kongera urupfu rw'uturemangingo muri selile yibibyimba ya FGFR-bikabije. FGFR ni reseptor tyrosine kinase ikenewe mugukwirakwiza kanseri yibibyimba, gutandukana no kubaho kandi imvugo yayo igengwa nubwoko bwinshi bwibibyimba. |
| CPDB1093 | Derazantinib; ARQ-087 | Derazantinib, izwi kandi ku izina rya ARQ-087, ni bioavailable yo mu kanwa ikumira fibroblast growth factor reseptor (FGFR) ifite ibikorwa bya antineoplastique. |
| CPDB0942 | BLU-554 | BLU-554 ni fibroblast yo gukura yibintu 4 (FGFR4) inhibitor ishobora kuvura kanseri ya hepatocellular na cholangiocarcinoma. |
| CPD0999 | H3B-6527 | H3B-6527 (H3 Biomedicine) ni inhibitori ya FGFR4 ihitamo cyane ibikorwa bya antitumour ikomeye muri FGF19 yongerewe umurongo wimbeba nimbeba. |
| CPD0997 | FGF401 | FGF-401 ni inhibitori ya FGFR4 yakuwe muri patenti WO2015059668A1, urugero rwa 83; ifite IC50 ya 1.9 nM. |
| CPDB0053 | AZD4547 | AZD 4547 ni inhibitori ya fibroblast yo gukura kwakirwa (FGFR) tyrosine kinase ifite IC50 ifite agaciro ka 0.2, 2.5, na 1.8 nM kuri FGFR1, 2, na 3. |
| CPD3610 | BLU-9931 | BLU9931 ninzitizi ikomeye, itoranya, kandi idasubirwaho FGFR4 inhibitor hamwe na IC50 ya 3 nM, hafi 297-, 184-, na 50 guhitamo inshuro kuri FGFR1 / 2/3. |
