FGF401

Izina ryimiti:

N- (5-cyano-4 - ((2-mikorerexyethyl) amino) pyridin-2-yl) -7-formyl-6 - ((4-methyl-2-oxopiperazin-1-yl) methyl) -3,4 -dihydro-1,8-naphthyridine-1 (2H) -carboxamide

Kode ya SMILES:

CN1CC (N (CC2 = CC (CCCN3C (NC4 = CC (NCCOC)) = C (C # N) C = N4) = O) = C3N = C2C = O) CC1) = O

InChi Code:

InChI = 1S / C25H30N8O4 / c1-31-7-8-32 (23 (35) 15-31) 14-18-10-17-4-3-6-33 (24 (17) 29-21 (18) 16-34) 25 (3 6) 30-22-11-20 (27-5-9-37-2) 19 (12-26) 13-28-22 / h10-11,13,16H, 3-9,14-15H2,1- 2H3, (H2,27,28,30,36)

InChi Urufunguzo:

BHKDKKZMPODMIQ-UHFFFAOYSA-N

Ijambo ryibanze:

FGF401, FGF-401, FGF 401, 1708971-55-4

Gukemura:Gukemura muri DMSO

Ububiko:0 - 4 ° C mugihe gito (iminsi kugeza ibyumweru), cyangwa -20 ° C mugihe kirekire (amezi).

Ibisobanuro:

FGF-401 ni inhibitori ya FGFR4 yakuwe muri patenti WO2015059668A1, urugero rwa 83; ifite IC50 ya 1.9 nM.

Intego: FGFR4