BAY-293

Izina ryimiti:

(R) -6,7-dimethoxy-2-methyl-N- (1- (4- (2 -

Kode ya SMILES:

C [C @@ H] (NC1 = C2C = C (OC) C (OC) = CC2 = NC (C) = N1) C3 = CC (C4 = CC = CC = C4CNC) = CS3

InChi Code:

InChI = 1S / C25H28N4O2S / c1-15 (24-10-18 (14-32-24) 19-9-7-6-8-17 (19) 13-26-3) 27-25-20-11- 22 (30-4) 23 (31-5) 12-21 (20) 28-16 (2) 29-25 / h6-12,14-15,26H, 13H2,1-5H3, (H, 27,28 , 29) / t15- / m1 / s1

InChi Urufunguzo:

WEGLOYDTDILXDA-OAHLLOKOSA-N

Ijambo ryibanze:

BAY-293, BAY 293, BAY293

Gukemura: 

Ububiko: 

Ibisobanuro:

BAY-293 ninzitizi ikomeye ya SOS1 ibuza gukora RAS binyuze mu guhagarika imikoranire ya RAS-SOS1. BAY-293) ihitamo guhitamo imikoranire ya KRAS-SOS1 na IC50 ya 21 nM kandi ni iperereza ryimiti ryiperereza ryigihe kizaza.

Intego: SOS1 inhibitor