DEL-22379
Tsatanetsatane wa Zamalonda
Zolemba Zamalonda
| Paketi Kukula | Kupezeka | Mtengo (USD) |
| 100 mg | Zilipo | 350 |
| 250 mg | Zilipo | 600 |
| 1g | Zilipo | 1200 |
| Makulidwe Enanso | Pezani Mawu | Pezani Mawu |
Dzina la Chemical:
(Z)-N-(3-((5-methoxy-1H-indol-3-yl)methylene)-2-oxoindolin-5-yl)-3-(piperidin-1-yl)propanamide
SMILES Kodi:
O=C(NC1=CC2=C(NC(/C2=C/C3=CNC4=C3C=C(OC)C=C4)=O)C=C1)CCN5CCCCC5
InChi kodi:
InChI=1S/C26H28N4O3/c1-33-19-6-8-23-20(15-19)17(16-27-23)13-22-21-14-18(5-7-24(21) 29-26 (22) 32)28-25(31)9-12-30-10-3-2-4-11-30/h5-8,13-16,27H,2-4,9-12H2,1H3,(H,28 ,31)(H,29,32)/b22-13+
InChi Key:
INQUULPSXCZAKMS-LPYMAVHISA-N
Mawu ofunika:
DEL-22379, DEL22379, DEL 22379, 181223-80-3
Kusungunuka:Zosungunuka mu DMSO
Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi)
Kufotokozera:
DEL-22379 ndi yamphamvu komanso yosankha ERK Dimerization inhibitor. DEL-22379 imaletsa ERK Dimerization popanda kukhudza ERK phosphorylation, imateteza tumorigenesis yoyendetsedwa ndi RAS-ERK pathway oncogenes. Pafupifupi 50% ya zilonda zaumunthu zimasonyeza kusalongosoka kwa RAS-ERK; kuletsa ndi njira yovomerezeka yothandizira antineoplastic.
Cholinga: ERK
