LX-2761
Tsatanetsatane wa Zamalonda
Zogulitsa Tags
| Paketi Kukula | Kupezeka | Mtengo (USD) |
| 100 mg | Zilipo | 500 |
| 500 mg | Zilipo | 800 |
| 1g | Zilipo | 1200 |
| Makulidwe Enanso | Pezani Mawu | Pezani Mawu |
Dzina la Chemical:
N-(1-((2-(Dimethylamino)ethyl) amino)-2-methyl-1-oxopropan-2-yl)-4-(4-(2-methyl-5-((2S,3R,4R), 5S,6R) -3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)benzyl)phenyl) -butanamide
SMILES Kodi:
O=C(NC(C)(C)C(NCCN(C)C)=O)CCCC1=CC=C(CC2=CC([C@H]3[C@H](O)[C@@ H](O)[C@H](O)[C@@H](SC)O3)=CC=C2C)C=C1
InChi kodi:
InChI=1S/C32H47N3O6S/c1-20-10-15-23(29-27(38)26(37)28(39)30(41-29)42-6)19-24(20)18-22- 13-11-21(12-14-22)8-7-9-25(36)3 4-32(2,3)31(40)33-16-17-35(4)5/h10-15,19,26-30,37-39H,7-9, 16-18H2,1-6H3,(H,33,40)(H,34,36)/t26-,27-,28+,29+,30-/m1/s1
InChi Key:
BNPZTRDIESRGTC-IXYVTWBDSA-N
Mawu ofunika:
LX-2761, LX2761, LX 2761, 1610954-97-6
Kusungunuka:Zosungunuka mu DMSO
Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi).
Kufotokozera:
LX2761 ndi SGLT1 inhibitor yomwe imagwira ntchito kwanuko yomwe ili yamphamvu kwambiri mu vitro ndipo imachedwetsa kuyamwa kwa shuga m'matumbo mu vivo kuti glycemic control. LX2761 ili ndi hSGlt1 2.2 nM; hSGLT2 2.7 nM ndi F% =<2. LX2761 ndi molekyulu yamphamvu kwambiri, yokhazikika pamankhwala, komanso yocheperako yomwe idapeza umboni wamalingaliro mu OGTT pamilingo yotsika kwambiri. LX2761 idapangidwa kuti ikhalebe m'matumbo pambuyo pobereka m'kamwa kuti iletse SGLT1 kwanuko popanda kukhudza njira ya SGLT1/2 mu impso.
Zolinga: SGLT1
