AMG-510
Tsatanetsatane wa Zamalonda
Zolemba Zamalonda
| Paketi Kukula | Kupezeka | Mtengo (USD) |
| 1g | zilipo | 1300 |
| 5g | zilipo | 6000 |
| 10g pa | zilipo | 10500 |
Dzina la Chemical:
4-((S) -4-acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl) )pyrido[2,3-d]pyrimidin-2(1H)-chimodzi
SMILES Kodi:
O=C(C=C)N1C[C@H](C)N(C2=NC(N(C3=C(C)C=CN=C3C(C)C)C4=C2C=C(F)C (C5=C(O)C=CC=C5F)=N4)=O)CC1
InChi kodi:
InChI=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8- 7-9-22 (24)39)34 -29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6-11,14,16,18,39H,1 ,12-13,15H2,2-5H3/t18-/m0/s1
InChi Key:
NXQKSXLFSAEQCZ-SFHVURJKSA-N
Mawu ofunika:
AMG-510; AMG 510; AMG510
Kusungunuka:
Posungira:
Kufotokozera:
AMG-510 ndi wamphamvu KRAS G12C covalent inhibitor. AMG-510 imayang'ana mosankha KRAS p.G12C mutant, pamlingo wa DNA, RNA kapena puloteni, ndikuletsa, kudzera m'njira yomwe sinadziwikebe, kuwonetsa ndi/kapena ma cell a chotupa kudzera mu KRAS p.G12C mutant. Izi zitha kulepheretsa kukula kwa maselo a chotupa a KRAS p.G12C
Cholinga: KRAS
