Omarigliptin

Ingoa matū:

(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)tetrahydro-2H -pyran-3-amine

Waehere SMILES:

N[C@@H]1[C@@H](C2=CC(F)=CC=C2F)OC[C@H](N3CC4=NN(S(=O)(C)=O)C= C4C3)C1

Waehere InChi:

InChI=1S/C17H20F2N4O3S/c1-27(24,25)23-7-10-6-22(8-16(10)21-23)12-5-15(20)17(26-9-12) 13-4-11(18)2-3-14(13)19/h2-4,7,12,15,17H,5-6,8-9,20H2,1H3/t12-,15+,17- /m1/s1

Kī InChi:

MKMPWKUAHLTIBJ-ISTRZQFTSA-N

Kupumatua:

Omarigliptin,MK-3102,MK3102,Marizev,1226781-44-7

Wairewa:Wairewa i roto i te DMSO

Rokiroki:0 - 4°C mo te wa poto (ra ki nga wiki), -20°C ranei mo te wa roa (marama)

Whakaahuatanga:

Ko Omarigliptin, e mohiotia ana ko MK-3102, he aukati DPP-4 kaha me te roa mo te maimoatanga kotahi-wiki mo te mate huka momo 2. Ko te MK-3102 (omarigliptin), i tohuhia he aukati kaha me te whiriwhiri i te dipeptidyl peptidase 4 (DPP-4) me tetahi tohu rongoa pai mo te horopeta tangata kotahi-wiki ka tohua hei kaitono whanaketanga haumanu. Ko Omarigliptin kei te waahanga 3 te whanaketanga haumanu.

Whāinga: DPP-4