BAV-293

Nomen chemicum:

(R) -6,7-dimethoxy-2-methyl-N-(1-(4-(2-((methylamino)methyl)phenyl)thiophen-2-yl)ethyl)quinazolin-4-amine

SMILES Code:

C[C@@H](NC1=C2C=C(OC)C(OC)=CC2=NC(C)=N1)C3=CC(C4=CC=CC=C4CNC)=CS3

InChi Code:

InChI=1S/C25H28N4O2S/c1-15(24-10-18(14-32-24)19-9-7-6-8-17(19)13-26-3)27-25-20-11- 22(30-4)23(31-5)12-21(20)28-16(2)29-25/h6-12,14-15,26H,13H2,1-5H3,(H,27,28; ,29)/t15-/m1/s1

InChi Key:

WEGLOYDTDILXDA-OAHLLOKOSA-N

Keyword:

BAV 293, BAY 293, BAY293

Solubilitas: 

Repono: 

Descriptio:

BAY-293 potens est inhibitor SOS1 qui impedit activationem RAS per distractionem commercii RAS-SOS1. BAY-293) selective KRAS-SOS1 commercium cum IC50 21 nm vetat et est perutile chemicum specillum ad futuras inquisitiones.

Target: SOS1 inhibitor