LX-2761

LX-2761
  • Nomen:LX-2761
  • Catalogue No.CPDA1553
  • CAS No.:1610954-97-6
  • Pondus hypotheticum:601.803
  • Formulae chemica:C32H47N3O6S
  • Investigationes scientificae tantum, non aegros.

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    Nomen chemicum:

    N-((2-(2-(Dimethylamino)ethyl)amino)-2-methyl-1-oxopropan-2-yl)-4-(4-(2-methyl-5-((2S,3R,4R; 5S,6R)-3,4,5-trihydroxy-6-(methylthio) tetrahydro-2H-pyran-2-yl)benzyl)phenyl)-butanamide

    SMILES Code:

    O=C(NC(C)(C)C(NCCN(C)C)=O)CCCC1=CC=C(CC2=CC([C@H]3[C@H](O)[C@@ H](O)[C@H](O)[C@@H](SC)O3)=CC=C2C)C=C1

    InChi Code:

    InChI=1S/C32H47N3O6S/c1-20-10-15-23(29-27(38)26(37)28(39)30(41-29)42-6)19-24(20) 18-22- 13-11-21(12-14-22)8-7-9-25(36)3 . 4-32(2,3)31(40)33-16-17-35(4)5/h10-15,19,26-30,37-39H,7-9,16-18H2,1-6H3; (H,33,40)(H,34,36)/t26-,27-,28+,29+,30-/m1/s1

    InChi Key:

    BNPZTRDIESRGTC-IXYVTWBDSA-N

    Keyword:

    LX-2761, LX2761, LX 2761, 1610954-97-6 .

    Solubilitas:Solutum in DMSO

    Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).

    Descriptio:

    LX2761 localiter agens GLT1 inhibitor, qui in vitro et moras glucosi intestinalis effusio in vivo ad imperium glycemicum emendandum plurimum valet. LX2761 habet hSGLt1 2.2 nM; hSGLT2 2.7 nM et F% =<2. LX2761 validissima, chemica stabilis, moleculae luminaliter restricta, quae conceptus in OGTT dosibus infimis probationem consecutus est. LX2761 destinatum est ut in intestino remanere post partum oralem inhibere GLT1 localiter sine afficiens mechanismum GLT1/2 in renibus.

    Target: SGLT1


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