AZD-5069
Product Detail
Product Tags
| Pack Size | Availability | Pretium (USD) |
| 100mg | In Stock | 500 |
| 500mg | In Stock | 800 |
| 1g | In Stock | 1200 |
| Plus Sizes | Get Quotes | Get Quotes |
Nomen chemicum:
N-(2-((2,3-difluorobenzyl)thio)-6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)pyrimidin-4-yl)azetidine-1-sulfonamide
SMILES Code:
O=S(N1CCC1)(NC2=NC(SCC3=CC=CC(F)=C3F)=NC(O[C@H](C)[C@@H](O)CO)=C2)=O
InChi Code:
InChI=1S/C18H22F2N4O5S2/c1-11(14(26)9-25)29-166-8-15(23-31(27,28)24-6-3-7-24)21-18(22- 16) 30-1 0-12-4-2-5-13(19)17(12)20/h2,4-5,8,11,14,25-26H,3,6-7,9-10H2,1H3,(H ,21,22,23)/t11-,14+/m1/s1
InChi Key:
QZECRCLSIGFCIO-RISCZKNCSA-N
Keyword:
AZD-5069, AZD5069, AZD 5069, 878385-84-3
Solubilitas:Solutum in DMSO
Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).
Descriptio:
AZD-5069 potens et selectivus CXCR2 adversarius est cum potentia ne migrationem neutrophilam in aenigmate patientibus cum COPD inhibeat. AZD-5069 ostensum est inhibere ligaturam radiolabellorum CXCL8 ad CXCR2 humanam cum valore pIC50 9.1. Praeterea AZD5069 neutrophil chemotaxis inhibetur cum pA2 proxime 9.6, et adhaesio moleculae expressionis cum pA2 ipsius 6.9, in responsione ad CXCL1. AZD5069 lente convertitur antagonista CXCR2 cum effectibus temporis et temperationis evidentis in pharmacologia et machinis ligaturae. AZD-5069 etiam potentia utilis est ad condiciones inflammationis patientis.
Target: CXCR2