Vactosertib

Vactosertib
  • Nomen:Vactosertib
  • Catalogue No.CPD3325
  • CAS No.:1352608-82-2
  • Pondus hypotheticum:399.42
  • Formulae chemica:C22H18FN7
  • Investigationes scientificae tantum, non aegros.

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    Nomen chemicum:

    N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl) -5-(6-methylpyridin-2-yl) methyl. )-2-fluoroaniline

    SMILES Code:

    FC1=CC=CC=C1NCC2=NC(C3=CN4C(C=C3)=NC=N4)=C(C5=NC(C)=CC=C5)N2

    InChi Code:

    InChI=1S/C22H18FN7/c1-14-5-4-8-18(27-14)22-21(15-9-10-20-25-13-26-30(20)12-15)28- 19(29-22)11-24-17-7-3-2-6-16(17)23/h2-10,12-13,24H,11H2,1H3,(H,28,29)

    InChi Key:

    FJCDSQATIJKQKA-UHFFFAOYSA-N

    Keyword:

    Vactosertib, EW-7197, EW7197, EW 7197, 1352608-82-2

    Solubilitas:Solutum in DMSO

    Repono:0 - 4° C pro brevi termino (dies ad hebdomades), vel -20° C ad terminum longum (menses)

    Descriptio:

    Vactosertib, etiam nota quod EW-7197 est potentior ALK5 inhibitor. EW-7197 potentem in actione anti-metastatica vivo ostendit, eius potentialem ad usum anti-cancri therapiae significans. EW-7197 nia TGF-β/Smad significationis. EW-7197 tumorem cellulae migrationis et incursus abrogat TGF-β1 . EW-7197 inhibet metastasim cancer pectoris ad lung. EW-7197 vetat metastasim et auget actionem cytotoxici T lymphocytis (CTLs) in 4T1 orthotopico murium inserti.

    Target: ALK


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