AMG-510
Product Detail
Product Tags
| Pack Size | Availability | Pretium (USD) |
| 1g | in stirpe | 1300 |
| 5g | in stirpe | 6000 |
| 10g | in stirpe | 10500 |
Nomen chemicum:
4-((S) -4-acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl )pyrido[2,3-d]pyrimidin-2(1H)-one
SMILES Code:
O=C(C=C)N1C[C@H](C)N(C2=NC(N(C3=C(C)C)C=CN=C3C(C)C)C4=C2C=C(F)C (C5=C(O)C=CC=C5F)=N4)=O)CC1
InChi Code:
InChI=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8- 7-9-22(24)39)34 . -29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6-11,14,16,18,39H,1 ,12-13,15H2,2-5H3/t18-/m0/s1
InChi Key:
NXQKSXLFSAEQCZ-SFHVURJKSA-N
Keyword:
AMG-DX; AMG 510; AMG510
Solubilitas:
Repono:
Descriptio:
AMG-510 potens est KRAS G12C inhibitor covalent. AMG-510 selectas KRAS p.G12C mutant, vel DNA, RNA vel interdum campestri, et impedit, per quasi nondum elucidatum, expressionem vel tumorem cellularum per KRAS p.G12C mutant significans. Hoc incrementum in KRAS p.G12C exprimens cellulis tuberculum inhibere potest
Target: KRAS
