CP-456773 sodium
Product Detail
Product Tags
| Pack Size | Availability | Pretium (USD) |
| 100mg | In Stock | 500 |
| 500mg | In Stock | 800 |
| 1g | In Stock | 1200 |
| Plus Sizes | Get Quotes | Get Quotes |
Nomen chemicum:
sodium (1,2,3,5,6,7-hexahydro-s-indacen-4-yl) carbamoyl)((4-(2-hydroxypropan-2-yl) furan-2-yl)sulfonyl)amide
SMILES Code:
O=S(C1=CC(C(C)(O)C)=CO1)([N-]C(NC2=C3CCCC3=CC4=C2CCC4)=O)=O.[Na+]
InChi Code:
InChI=1S/C20H24N2O5S.Na/c1-20(2,24)14-10-17(27-11-14)28(25,26)22-19(23)21-18-15-7-3- 5-12(15)9-13-6-4-8-16(13)18;/h9-11,24H,3-8H2,1-2H3,(H2,21,22,23);/q; +1/p-1
InChi Key:
LFQQNXFKPNZRFT-UHFFFAOYSA-M
Keyword:
MCC950, MCC 950, MCC-950, CP-45677, CP45677, CP 45677, CRID-3, CRID3, CRID 3, CP-456773 sal sodium, Cytokine emissio medicamento inhibitoriae 3, 256373-96-3
Solubilitas:Solutum in DMSO
Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).
Descriptio:
CP-456773, quae etiam MCC950 et CRID3 nota est, potens et selectiva emissio cytokini inhibitoris et NLRP3 inhibitor inflammatorius ad morbos inflammationes curandos. CP-456773 vetat interleukin 1β (IL-1β) secretio et processus caspase 1 . MCC950 obstruxit activationem canonicam et noncanonicam NLRP3 ad concentrationes nanomolares. MCC950 nominatim inhibuit activationem NLRP3 sed non AIM2, NLRC4 vel NLRP1 inflammasomes. MCC950 interleukin-1β (IL-1β) productio in vivo et attenuata severitatem autoimmune encephalomyelitis experimentalis (EAE), morbi exemplar multiplex sclerosis. MCC950 est potentia therapeutica pro NLRP3-consociata syndromis, inclusis morbis autoinflammatoriis et autoimmunerum, et instrumentum ulterioris studii NLRP3 inflammasimi in sanitate et morbo humano.
Target: NLRP3
