BAY-293
Nkọwa ngwaahịa
Mkpado ngwaahịa
| Nha ngwugwu | Nnweta | Ọnụ ego (USD) |
Aha kemịkalụ:
(R) -6,7-dimethoxy-2-methyl-N- (1- (4- (2- ((methylamino)methyl) phenyl) thiophen-2-yl) ethyl) quinazolin-4-amine
Koodu Ọchịchọ:
C[C@@H](NC1=C2C=C(OC)C(OC)=CC2=NC(C)=N1)C3=CC(C4=CC=CC=CC=C4CNC)=CS3
Koodu InChi:
InChi=1S/C25H28N4O2S/c1-15(24-10-18(14-32-24)19-9-7-6-8-17(19)13-26-3)27-25-20-11- 22 (30-4) 23 (31-5) 12-21 (20)28-16 (2)29-25/h6-12,14-15,26H,13H2,1-5H3, (H,27,28 ,29)/t15-/m1/s1
Igodo InChi:
WEGLOYDTDILXDA-OAHLLOKOSA-N
Okwu:
BAY-293, BAY 293, BAY293
Solubility:
Nchekwa:
Nkọwa:
BAY-293 bụ ihe mgbochi SOS1 siri ike nke na-egbochi ịgbalite RAS site na imebi mmekọrịta RAS-SOS1. BAY-293) na-akpachapụ anya na-egbochi mmekọrịta KRAS-SOS1 na IC50 nke 21 nM ma bụrụ nyocha kemịkalụ bara uru maka nyocha n'ọdịnihu.
Ebumnuche: ihe mgbochi SOS1
