Ozanimod

Aha kemịkalụ:

(S) -5- (3- (1- (2-hydroxyethyl) amino) -2,3-dihydro-1H-inden-4-yl) -1,2,4-oxadiazol-5-yl) -2 - isopropoxybenzonitrile

Koodu Ọchịchọ:

N#CC1=CC(C2=NC(C3=CC=CC4=C3CC[C@@H]4NCCO)=NO2)=CC=C1OC(C)C

Koodu InChi:

InChi=1S/C23H24N4O3/c1-14(2)29-21-9-6-15(12-16(21)13-24)23-26-22(27-30-23)19-5-3- 4-18-17 (19)7-8-20(18)25-10-11-28/h3-6,9,12,14,20,25,28H,7-8,10-11H2,1- 2H3/t20-/m0/s1

Igodo InChi:

XRVDGNKRPOAQTN-FQEVSTJZSA-N

Okwu:

Ozanimod, RPC-1063, RPC1063, RPC 1063, 1306760-87-1

Solubility:Soluble na DMSO

Nchekwa:0 - 4 Celsius C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 Celsius maka ogologo oge (ọnwa).

Nkọwa:

Ozanimod bụ onye ahọpụtara, onye na-ahụ maka ọnụ nke ndị na-anabata sphingosine-1-phosphate (S1P) S1P1 na SIP5. Ọ na-ebute ntinye nke S1P1, na-ebelata na-ekesa B na CCR7 (+) lymphocytes T, ma na-ebelata mbufụt na usoro ọrịa na ụdị ọrịa autoimmune atọ.1 Ozanimod nọ na ule ụlọ ọgwụ maka nlọghachite multiple sclerosis na ulcerative colitis.

Ebumnuche: S1P