LX-2761
Pwodwi detay
Tags pwodwi
| Gwosè pake | Disponibilite | Pri (USD) |
| 100 mg | Nan Stock | 500 |
| 500 mg | Nan Stock | 800 |
| 1g | Nan Stock | 1200 |
| Plis gwosè | Jwenn Quotes | Jwenn Quotes |
Non Chimik:
N-(1-((2-(Dimethylamino)etil)amino)-2-methyl-1-oxopropan-2-yl)-4-(4-(2-methyl-5-((2S,3R,4R), 5S,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)benzyl)phenyl)-butanamide
Kòd SMILES:
O=C(NC(C)(C)C(NCCN(C)C)=O)CCCC1=CC=C(CC2=CC([C@H]3[C@H](O)[C@@) H](O)[C@H](O)[C@@H](SC)O3)=CC=C2C)C=C1
Kòd InChi:
InChI=1S/C32H47N3O6S/c1-20-10-15-23(29-27(38)26(37)28(39)30(41-29)42-6)19-24(20)18-22- 13-11-21(12-14-22)8-7-9-25(36)34-32(2,3)31(40)33-16-17-35(4)5/h10-15, 19,26-30,37-39H,7-9,16-18H2,1-6H3,(H,33,40)(H,34,36)/t26-,27-,28+,29+,30 -/m1/s1
InChi kle:
BNPZTRDIESRGTC-IXYVTWBDSA-N
Mot:
LX-2761, LX2761, LX 2761, 1610954-97-6
Solibilite:Soluble nan DMSO
Depo:0 - 4 ° C pou kout tèm (jou a semèn), oswa -20 ° C pou tèm long (mwa).
Deskripsyon:
LX2761 se yon inibitè SGLT1 ki aji lokalman ki trè pisan nan vitro epi ki retade absòpsyon glikoz entesten an vivo pou amelyore kontwòl glisemi. LX2761 gen hSGLt1 2.2 nM; hSGLT2 2.7 nM ak F% =<2. LX2761 se yon molekil trè pisan, ki estab chimikman, epi ki gen restriksyon sou limyè ki te reyalize prèv konsèp nan OGTT nan dòz ki ba anpil. LX2761 te fèt pou rete nan trip la apre livrezon oral pou anpeche SGLT1 lokalman san yo pa afekte mekanis SGLT1/2 nan ren an.
Sib: SGLT1
