GDC-0077
Pwodwi detay
Tags pwodwi
| Gwosè pake | Disponibilite | Pri (USD) |
| 100 mg | Nan Stock | 500 |
| 500 mg | Nan Stock | 800 |
| 1g | Nan Stock | 1200 |
| Plis gwosè | Jwenn Quotes | Jwenn Quotes |
Non Chimik:
(S)-2-((2-((S)-4-(difluorometil)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4 ]oxazepin-9-yl)amino)propanamid
Kòd SMILES:
C[C@@H](C(N)=O)NC1=CC=C(C2=NC(N3[C@H](C(F)F)COC3=O)=CN2CCO4)C4=C1
Kòd InChi:
InChI=1S/C18H19F2N5O4/c1-9(16(21)26)22-10-2-3-11-13(6-10)28-5-4-24-7-14(23-17(11) 24)2 5-12(15(19)20)8-29-18(25)27/h2-3,6-7,9,12,15,22H,4-5,8H2,1H3,(H2,21,26 )/t9-,12-/m0/s1
InChi kle:
SGEUNORSOZVTOL-CABZTGNLSA-N
Mot:
GDC-0077, GDC0077, GDC 0077, 2060571-02-8
Solibilite:Soluble nan DMSO
Depo:0 - 4 ° C pou kout tèm (jou a semèn), oswa -20 ° C pou tèm long (mwa).
Deskripsyon:
GDC-0077 se yon inibitè PI3K oralman disponib ak selektif (IC50 = 0.038 + 0.003 nM) ak > 300-pliye selektif sou lòt klas I PI3K izoform. GDC-0077 egzèse aktivite li pa obligatwa nan sit la obligatwa ATP nan PI3K, kidonk anpeche fosforilasyon PIP2 a PIP3.
Sib: PI3K
