BAY-293

Inoa Kimia:

(R)-6,7-dimethoxy-2-methyl-N-(1-(4-(2-((methylamino)methyl)phenyl)thiophen-2-yl)ethyl)quinazolin-4-amine

SMILES Code:

C[C@@H](NC1=C2C=C(OC)C(OC)=CC2=NC(C)=N1)C3=CC(C4=CC=CC=C4CNC)=CS3

Code InChi:

InChI=1S/C25H28N4O2S/c1-15(24-10-18(14-32-24)19-9-7-6-8-17(19)13-26-3)27-25-20-11- 22(30-4)23(31-5)12-21(20)28-16(2)29-25/h6-12,14-15,26H,13H2,1-5H3,(H,27,28 ,29)/t15-/m1/s1

Ki InChi:

WEGLOYDTDILXDA-OAHLLOKOSA-N

huaʻōlelo:

BAY-293, BAY 293, BAY293

Hiki ke hoʻoheheʻe: 

Waihona: 

wehewehe:

ʻO BAY-293 kahi mea hoʻopaneʻe SOS1 ikaika e ālai i ka hoʻoulu ʻana o RAS ma o ka hoʻopau ʻana i ka pilina RAS-SOS1. BAY-293) koho i ka pilina KRAS-SOS1 me kahi IC50 o 21 nM a he noiʻi kemika waiwai no nā noiʻi e hiki mai ana.

Pahuhopu: SOS1 inhibitor