ARS-1620
Huahana Huahana
Huahana Huahana
| Nui Puke | Loaʻa | Kumukuai (USD) |
| 100mg | Loaʻa | 800 |
| 500mg | Loaʻa | 1500 |
| 1g | Loaʻa | 2000 |
| Nui hou aku | E kiʻi i nā huaʻōlelo | E kiʻi i nā huaʻōlelo |
Inoa Kimia:
(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one
SMILES Code:
C=CC(=O)N1CCN(CC1)C2=C3C=C(C(=C4C(=O)C=CC=C4F)C(=C3NC=N2)F)Cl
Code InChi:
InChI=1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17(19(24)20(12)25- 11-26-21)18-14(23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2
Ki InChi:
QIQWMIZVWVSRAS-UHFFFAOYSA-N
Hua'ōlelo:
ARS-1620, KRAS G12C, NSCLC, ARS1620, ARS 1620, KRASG12C, 1698055-85-4
Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia ma DMSO
Waihona:0 - 4°C no ka wā pōkole (nā lā i nā pule), a i ʻole -20°C no ka wā lōʻihi (mau mahina)
wehewehe:
ʻO ARS-1620 kahi prodrug i hoʻolālā ʻia mai ka ARS-853, kahi mea hoʻopale S-IIP G12C ikaika a koho. Manaʻo ʻia ʻo ARS-1620 he hoʻolālā lapaʻau no ka p.G12C KRAS mutant cancers.
Pahuhopu: KRAS (K-Ras G12C)
