Saukewa: MC180295

Saukewa: MC180295
  • Suna:Saukewa: MC180295
  • Catalog No.:Saukewa: CPD100908
  • Lambar CAS:2237942-08-2
  • Nauyin Kwayoyin Halitta:358.11
  • Tsarin Sinadarai:Saukewa: C17H18N4O3S
  • Don binciken kimiyya kawai, ba ga marasa lafiya ba.

    Cikakken Bayani

    Tags samfurin

    Girman Kunshin samuwa Farashin (USD)

    Sunan Sinadari:

    Rel- (4-amino-2-((2S)-bicyclo[2.2.1] heptan-2-yl) amino) thiazol-5-yl (2-nitrophenyl) methanone

    Lambar SMILES:

    O=C(C1=C(N)N=C(N[C@@H]2C(C3)CCC3C2)S1)C4=CC=CC=C4[N+]([O-])=O

    Lambar InChi:

    InChi=1S/C17H18N4O3S/c18-16-15(14(22)11-3-1-2-4-13(11)21(23)24)25-17(20-16)19-12-8- 9-5-6-10(12)7-9/h1-4,9-10,12H,5-8,18H2,(H,19,20)/t9?,10?,12-/m0/s1

    InChi Key:

    JRNXAQINDCOHGS-CBINBANVSA-N

    Mabuɗin kalma:

    Solubility: 

    Ajiya: 

    Bayani:

    MC180295 mai hanawa CDK9 ne mai zaɓin zaɓi (IC50 = 5 nM). (MC180295 yana da faffadan aikin rigakafin ciwon daji a cikin vitro kuma yana da tasiri a cikin nau'ikan ciwon daji na vivo. Bugu da ƙari, hana CDK9 yana da hankali ga mai hanawa na rigakafi α-PD-1 a cikin vivo, yana mai da shi kyakkyawan manufa don maganin ciwon daji na epigenetic.

    Saukewa: CDK9


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