diABZI STING agonist-1
Manylion Cynnyrch
Tagiau Cynnyrch
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Enw Cemegol:
(E)-1-(4-(5-carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido))-7-(3-morpholinopropoxy)-1H-benso[d]imidazol- 1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-methoxy-1H-benso[d]imidazole-5-carboxamide
Cod gwenu:
O=C(N)C1=CC(N=C(NC(C2=CC(C)=NN2CC)=O)N3C/C=C/CN4C(NC(C5=CC(C)=NN5CC)=O)) =NC6=C4C(OCCCN7CCOCC7)=CC(C(N)=O)=C6)=C3C(OC)=C1
Cod InChi:
InChI=1S/C42H51N13O7/c1-6-54-31(19-25(3)49-54)39(58)47-41-45-29-21-27(37(43)56)23-33( 60-5)35(29)52(41)12-8-9-13-53-36-30(46-42(53)48-40(59)32-20-26(4)50-55( 32)7-2) 22-28(38(44)57)24-34(36)62-16-10-11-51-14-17-61-18-15-51/h8-9,19- 24H,6-7,10-18H2,1-5H3,(H2,43,56)(H2,44,57)(H,45,47,58)(H,46,48,59)/b9-8 +
Allwedd InChi:
JGLMVXWAHNTPRF-CMDGGOBGSA-N
Allweddair:
Hydoddedd:
Storio:
Disgrifiad:
Mae diABZI STING agonist-1 yn symbylydd dethol o agonist derbynnydd genynnau interfferon (STING), gydag EC50s o 130, 186 nM ar gyfer dynol a llygoden, yn y drefn honno.
Targed: STING
