OGUN STING-4

Orukọ Kemikali:

1,1' (butane-1,4-diyl) bis (2- (1-ethyl-3-methyl-1H-pyrazole-5-carboxamido) -1H-benzo [d] imidazole-5-carboxamide)

KỌỌDỌ SMILES:

O=C(C1=CC=C2N(CCCCN3C(NC(C4=CC)=NN4CC)=O)=NC5=CC(C(N)=O)=CC=C35)C(NC(C6=CC) (C)=NN6CC)=O)=NC2=C1)N

Koodu InChi:

InChi=1S/C34H38N12O4/c1-5-45-27(15-19(3)41-45)31(49)39-33-37-23- 17-21 8) 18-24 (26) 38-34 (44) 40-32 (50) 28-16-20 (4) 42-46 (28) 6-2 / h9-12,15-18 H,5-8,13-14H2,1-4H3,(H2,35,47)(H2,36,48)(H,37,39,49)(H,38,40,50)

Bọtini InChi:

ICZSAXDKFXTSGL-UHFFFAOYSA-N

Koko-ọrọ:

Solubility: 

Ibi ipamọ: 

Apejuwe:

STING agonist-4 jẹ ohun iwuri ti Interferon Genes (STING) agonist olugba ti o han gbangba inhibitory igbagbogbo (IC50) ti 20 nM. STING agonist-4 jẹ amidobenzimidazole (ABZI) ti o ni ibatan si ami-ara meji lati ṣẹda ABZI (diABZI) ti o ni asopọ pẹlu imudara imudara si STING ati iṣẹ cellular

Àfojúsùn: STING