OGUN STING-3
Alaye ọja
ọja Tags
| Iwọn Pack | Wiwa | Iye owo (USD) |
Orukọ Kemikali:
(E) -1- (4- (5-carbamoyl-2---1-ethyl-3-methyl-1H-pyrazole-5-carboxamido) -1H-benzo [d] imidazol-1-yl) ṣugbọn-2- en-1-yl)-2- (1-ethyl-3-methyl-1H-pyrazole-5-carboxamido) -7- (3-hydroxypropoxy) -1H-benzo [d] imidazole-5-carboxamide
KỌỌDỌ SMILES:
O=C(N)C1=CC=C(N(C(NC(C2=CC(C))=NN2CC)=O)=N3)C/C=C/CN4C5=C(N=C4NC(C6=CC) (C)=NN6CC)=O)C=C(C(N)=O)C=C5OCCCO)C3=C1
Koodu InChi:
InChi=1S/C37H42N12O6/c1-5-48-28(16-21(3)44-48)34(53)42-36-40-25-18-23(32(38)51)10-11- 27(25)46(36)12-7-8-13-47-31-26(19-24(33(39)52)20-30(31)55-15-9-14-50)41- 37 (47)43-35 (54)29-17-22 (4)45-49(29)6-2/h7-8,10-11,16-20,50H,5-6,9,12- 15H2,1-4H3,(H2,38,51)(H2,39,52)(H,40,42,53)(H,41,43,54)/b8-7+
Bọtini InChi:
VHCDRDBBENBVEK-BQYQJAHWSA-N
Koko-ọrọ:
Solubility:
Ibi ipamọ:
Apejuwe:
STING agonist-3, ti a fa jade lati itọsi WO2017175147A1 (apẹẹrẹ 10), jẹ yiyan ati ti kii-nucleotide kekere-moleku STING agonist pẹlu pEC50 ati pIC50 ti 7.5 ati 9.5, lẹsẹsẹ. STING agonist-3 ni ipa egboogi-tumor ti o tọ ati agbara nla lati ni ilọsiwaju itọju ti akàn
Àfojúsùn: STING
