diABZI STING agonist-1 trihydrochloride

Orukọ Kemikali:

(E) -1- (4- (5-carbamoyl-2-- (1-ethyl-3-methyl-1H-pyrazole-5-carboxamido) -7- (3-morpholinpropoxy) -1H-benzo [d] imidazol- 1-yl) ṣugbọn-2-en-1-yl) -2- (1-ethyl-3-methyl-1H-pyrazole-5-carboxamido) -7-methoxy-1H-benzo [d] imidazole-5-carboxamide trihydrochloride

KỌỌDỌ SMILES:

O=C(N)C1=CC(N=C(NC(C2=CC(C)=NN2CC)=O)N3C/C=C/CN4C(NC(C5=CC(C)=NN5CC)=O) =NC6=C4C(OCCCN7CCOCC7)=CC(C(N)=O)=C6)=C3C(OC)=C1.Cl.Cl.Cl

Koodu InChi:

CKESNWHACHILIV-BILRHTGOSA-N

Bọtini InChi:

InChI=1S/C42H51N13O7.3ClH/c1-6-54-31(19-25(3)49-54)39(58)47-41-45-29-21-27(37(43)56)23- 33 (60-5) 35 (29) 52 (41) 12-8-9-13-53-36-30 (46-42 (53) 48-40 (59) 32-20-26 (4) 50- 55 (32)7-2)22-28 (38 (44)57)24-34 (36)62-16-10-11-51-14-17-61-18-15-51;;;/h8 -9,19-24H,6-7,10-18H2,1-5H3,(H2,43,56)(H2,44,57)(H,45,47,58)(H,46,48,59) );3*1H/b9-8+;;;

Koko-ọrọ:

Solubility: 

Ibi ipamọ: 

Apejuwe:

diABZI STING agonist-1 (trihydrochloride) jẹ apaniyan yiyan ti awọn jiini interferon (STING) agonist olugba, pẹlu EC50s ti 130, 186 nM fun eniyan ati asin, lẹsẹsẹ.

Àfojúsùn: STING