ARS-1620
Alaye ọja
ọja Tags
| Iwọn Pack | Wiwa | Iye owo (USD) |
| 100mg | O wa | 800 |
| 500mg | O wa | 1500 |
| 1g | O wa | 2000 |
| Awọn iwọn diẹ sii | Gba Awọn asọye | Gba Awọn asọye |
Orukọ Kemikali:
(S) -1- (4- (6-chloro-8-fluoro-7--2-fluoro-6-hydroxyphenyl) quinazolin-4-yl) piperazin-1-yl) prop-2-en-1-ọkan
KỌỌDỌ SMILES:
C=CC(=O)N1CCN(CC1)C2=C3C=C(C(=C4C(=O)C=CC=C4F)C(=C3NC=N2)F)Cl
Koodu InChi:
InChi=1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17( 19 (24)20 (12)25-11-26-21)18-14 (23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2
Bọtini InChi:
QIQWMIZVWVSRAS-UHFFFAOYSA-N
Koko-ọrọ:
ARS-1620, KRAS G12C, NSCLC, ARS1620, ARS 1620, KRASG12C, 1698055-85-4
Solubility:Tiotuka ni DMSO
Ibi ipamọ:0 - 4°C fun igba kukuru (ọjọ si awọn ọsẹ), tabi -20°C fun igba pipẹ (osu)
Apejuwe:
ARS-1620 jẹ prodrug ti a ṣe apẹrẹ lati ARS-853, eyiti o jẹ alagidi S-IIP G12C ti o lagbara ati yiyan. ARS-1620 ni a nireti lati jẹ ilana itọju ailera fun p.G12C KRAS awọn aarun alakan.
Àfojúsùn: KRAS (K-Ras G12C)
