Adavivint
Iinkcukacha zeMveliso
Iithegi zeMveliso
| Ubungakanani bePakethi | Ubukho | Ixabiso (USD) |
| 100mg | Ikhona evenkileni | 500 |
| 500mg | Ikhona evenkileni | 800 |
| 1g | Ikhona evenkileni | 1200 |
| Iisayizi ezininzi | Fumana iiQuotes | Fumana iiQuotes |
Igama leMchiza:
N-(5-{3--[7-(3-fluorophenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-5-yl}pyridin-3-yl)-3 -methylbutanamide
Ikhowudi yoncumo:
CC(C)CC(NC1=CC(C2=CC3=C(NN=C3C(N4)=NC5=C4C(C6=CC=CC(F)=C6)=CN=C5)C=C2)=CN= C1)=O
Ikhowudi ye-InChi:
InChI=1S/C29H24FN7O/c1-16(2)8-26(38)33-21-10-19(12-31-13-21)17-6-7-24-22(11-17)28( 37-36-24)29-34-25-15-32-14-23(27(25)35-29)18-4-3-5-20(30)9-18/h3-7,9- 16H,8H2,1-2H3,(H,33,38)(H,34,35)(H,36,37)
Isitshixo se-InChi:
AQDWDWAYVBQMAM-UHFFFAOYSA-N
Igama elingundoqo:
Adavivint, SM04690, SM-04690, SM 04690, 1467093-03-3
Ukunyibilika:Inyibilika kwi-DMSO
Ugcino:0 - 4°C ixesha elifutshane (iintsuku ukuya kwiiveki), okanye -20°C ixesha elide (iinyanga).
Inkcazo:
Inoveli imolekyuli encinci ye-Wnt pathway inhibitor ene-EC50 ye-3 nM in vitro; ibangela ukuhlukana kwe-hMSC kwii-chondrocytes ezikhulileyo, ezisebenzayo kunye nokunciphisa amanqanaba okumakisha i-cartilage catabolic; iphucula kakhulu i-Osteoarthritis Research Society International (OARSI) amanqaku e-histology kunye ne-biomarkers kwimodeli ye-OA ye-rodent.
Ithagethi: WNT
