Iqela lethu le-pharmacokinetic ligxile ekuphuhliseni kwangaphambili, ukuhlolwa kwe-DMPK kunye nokubhaliswa kwe-IND. Siye saseka iqonga elidityanisiweyo le-in vitro kunye ne-vivo screening technology ukuxhasa ukufunyanwa nophuhliso lweziyobisi. I-Caerulum Pharma inikezela ngenkonzo eguquguqukayo kunye neyomntu kwizisombululo zeDMPK ezisebenzayo nezingabizi kakhulu ukuqhubela phambili uphando lwakho.
1.Amacandelo okufunda
Iimolekyuli ezincinci, iimveliso zendalo, iipolypeptides.
2.Iinkonzo ezifumanekayo
I-Plasma / i-tissue protein binding assay
Umlinganiselo wePlasma kwigazi
Uzinzo lwe-metabolism ye-microsomal yesibindi
Ukuzinza kwisithuthi kunye neplasma
Ukuchongwa kweMetabolite
I-CYP reaction phenotyping
Inhibition yeCYP
3.Kulwakhiwo
Ukungeniswa kweHepatocyte
Caco-2 Permeability
UGT reaction phenotyping