CAT # | Igama lemveliso | Inkcazo |
CPD1573 | GDC-0077 | I-GDC-0077 yi-PI3K inhibitor ekhoyo ngomlomo enokuthi ibe nomsebenzi we-antineoplastic. |
CPD1022 | IPI-549 | I-IPI549 inamandla kwaye ikhetha i-PI3Kγ Inhibitor ene-IC50 ye-16 nM. |
CPDD3857 | GDC-0326 | I-GDC-0326 yi-inhibitor enamandla kwaye ekhethiweyo ye-α-Isoform ye-Phosphoinositide 3-Kinase (PI3Kalpha inhibitor). I-GDC-0326 ifikelela kwinqanaba eliphezulu kakhulu lokukhetha ngaphezu kwezinye i-kinases. I-GDC-0326 ine-plasma ephantsi ye-CL emntwini. |
CPDB0202 | I-AZD8186 | I-AZD8186 kunye ne-inhibitor ye-beta isoform ye-phosphoinositide-3 kinase (PI3K), kunye nomsebenzi onokuthi ube ne-antineoplastic. |
CPDB1536 | PQR530 | I-PQR530 yi-dual inhibitor enamandla kakhulu-PI3K/mTORC1/2. |
CPDB1573 | GDC-0077 | I-GDC-0077 ifumaneka ngomlomo kwaye ikhethiweyo ye-PI3K inhibitor (IC50 = 0.038 + 0.003 nM) kunye> 300-fold selective over other Class I PI3K isoforms. |