kwi-vivo Pharmacokinetic Assays

Iqela lethu le-pharmacokinetic ligxile ekuphuhliseni kwangaphambili, ukuhlolwa kwe-DMPK kunye nokubhaliswa kwe-IND. Siye saseka iqonga elidityanisiweyo le-in vitro kunye ne-vivo screening technology ukuxhasa ukufunyanwa nophuhliso lweziyobisi. I-Caerulum Pharma inikezela ngenkonzo eguquguqukayo kunye neyomntu kwizisombululo zeDMPK ezisebenzayo nezingabizi kakhulu.

1.Amacandelo okufunda

Iimolekyuli ezincinci, iimveliso zendalo, iipolypeptides.

2.Iinkonzo ezifumanekayo

Ukuhlolwa kwe-PK ekhawulezayo ngeendlela ezahlukeneyo zolawulo kwiimpuku kunye neentlobo ezingezizo, njengempuku, impuku, inja kunye nenkawu.

Ukuhanjiswa kwezicubu

Ukukhutshwa kunye nokulinganisela kobunzima

Isampula ye-CSF kunye nokungena kwe-BBB

Uphuhliso lwendlela yohlalutyo kwibhayoloji matrix

Uhlalutyo lobungakanani beesampulu ezahlukeneyo zebhayoloji

Ukusetyenzwa kwedatha kunye nokuhanjiswa

Uyilo lweprotocol enxulumene ne-3.DMPK kunye nokwenziwa ngokusekelwe kwimfuno yokufunda echaziweyo.


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