CAT # | Igama lemveliso | Inkcazo |
CPDB1974 | GSK-461364 | I-GSK461364 ixhomekeke kwidosi imisa ukukhwela ibhayisekile kweeseli kwiiseli zomhlaza ezandayo ezohlukeneyo kwaye, kwidosi ephezulu, ibangela i-apoptosis. Kubonakala ngathi isebenza ngakumbi ngokuchasene ne-p53-deficient tumors kwaye iyakwazi ukuwela umqobo wegazi-ubuchopho. I-GSK461364 iyasebenza kwi-vivo, ibangela inhibition yokukhula kwethumba okanye ukulibaziseka kokukhula kwiimodeli ze-xenograft kwiimpuku. |